I am interested in the development of novel antimicrobial agents targetted in virulence factors to cope with antibiotic resistance.
Bi C, Dong X, Zhong X, et al. (2016) Acacetin Protects Mice from Staphylococcus aureus Bloodstream Infection by Inhibiting the Activity of Sortase A. Molecules. 21, 1285.
Bi C, Wang L, Niu X, Cai H, et al. (2016) The use of chlorogenic acid and its analogues as inhibitors: an investigation of the inhibition of sortase A of Staphylococcus aureus using molecular docking and dynamic simulation. Biotechnol Lett. 0141-5492.
Wang L, Bi C, Cai H, Liu B, et al. (2015) The therapeutic effect of chlorogenic acid against Staphylococcus aureus infection through sortase A inhibition. Front Microbiol. 16;6:1031.
Wang L, Bi C, Wang T, et al. (2015) A coagulase-negative and non-haemolytic strain of Staphylococcus aureus for investigating the roles of SrtA in a murine model of bloodstream infection. Pathog Dis. 73(6):ftv042.
Liu B, Chen F, Bi C, et al. (2015) Quercitrin, an inhibitor of Sortase A, interferes with the adhesion of Staphylococcal aureus. Molecules. 20(4):6533-43.
Chen F, Liu B, Wang D, Wang L, Deng X, Bi C, et al. (2014) Role of sortase A in the pathogenesis of Staphylococcus aureus-induced mastitis in mice. FEMS Microbiol Lett. 351(1):95-103.
M.S. in Biochemistry and Molecular Biology, Jilin University, China, 2016
B.S. in Biotechnology, Jilin University, China, 2013