I am interested in understanding host-parasite interactions mediated by Toxoplasma and Plasmodium apicomplexa parasites using functional genomics.
Selected Publications
Plasmodium falciparum Rab5B is an N-terminally myristoylated Rab GTPase that is targeted to the parasite's plasma and food vacuole membranes. Carinne Ndjembo Ezougou, Fathia Ben-Rached, David Moss, Jing-wen Lin, Sally Black, Ellen Knuepfer, Judith Green, Shahid Khan, Amitabha Mukhopadhyay, Chris Janse, Isabelle Coppens, Hélène Year, Anthony Holder, Gordon Langsley. PLoS One. 2014 Feb.
Plasmodium falciparum ATG8 implicated in both autophagy and apicoplast formation. Andrew M. Tomlins, Fathia Ben Rached, Roderick A.M. Williams, William R. Proto, Isabelle Coppens, Ulrike Ruch, Tim W. Gilberger,Graham H. Coombs, Jeremy C. Mottram, Sylke Müller, Gordon Langsley. Autophagy 2013; 9:68 – 67.
Construction of a Plasmodium falciparum Rab-interactome identifies CK1 and PKA as Rab-effector kinases in malaria parasites. Fathia Ben Rached, Carinne Ndjembo-Ezougou, Syama Chandran, Hana Talabani, Hélène Yera, Vrushali Dandavate, Pierre Bourdoncle, Markus Meissner, Utpal Tatu and Gordon Langsley. Biology of the Cell Janv 2012.
Rab11A-controlled assembly of the inner membrane complex is required for completion of apicomplexan cytokinesis. Agop-Nersesian C, Naissant B, Ben Rached F, Rauch M, Kretzschmar A, Thiberge S, Menard R, Ferguson DJ, Meissner M, Langsley G. PLoS Pathog. Jan 2009.
Book Chapters
Rab proteins. Fathia Ben Rached & Gordon Langsley. Encyclopedia of Malaria. Springer New York, 2014.
Education
Ph.D. in Microbiology, Paris Diderot University, Paris, France, 2011.
M.Sc. in Molecular & Cellular Biology, Pierre et Marie Curie University, Paris, France, 2007.