Dr. Shuaib's current research interests include host-pathogen epigenomic interactions, functional genomics, and non-coding RNA. 

• SARS-CoV-2 genomes from Saudi Arabia implicate nucleocapsid mutations in host response and increased viral load (2022). Mourier T*, Shuaib M* Hala S*, Mfarrej S*, Alofi F, Naeem R, Alsomali A, Jorgensen D, Subudhi AM, Rached FB, Guan Q, Salunke RP, Ooi A, Esau L, Douvropoulou O, Nugmanova R, Perumal S, Zhang H, Rajan I, Al-Omari A, Salih S, Shamsan A, Mutair A A, Taha J, Alahmadi A, Khotani N, Alhamss A, Mahmoud A, Alquthami A, Dageeg A, Khogeer A, Hashem AM, Moraga P, Volz E, Almontashiri N, Pain A. Nature Communication,13:601 | https://doi.org/10.1038/s41467-022-28287-8 (*Equal first author)
• Ago1 controls myogenic differentiation by regulating eRNA mediated CBP guided epigenome reprogramming (2021). Fallatah B*, Shuaib M*, Adroub S.A, Paytuví-Gallart A, Della Valle F, Nadeef S, Lanzuolo C, Orlando V. Cell Report. 37 (9): 110066 https://doi.org/10.1016/j.celrep.2021.110066 (*Equal first author)
• Nuclear AGO1 Regulates Gene Expression by Affecting Chromatin Architecture in Human Cells. (2019). Shuaib M, Parsi K.M, Adroub SA, Thimma M, Hideya K, Seridi L, Carninci P, Orlando V. Cell Systems.9 (5): 446-458.e6. 
• Ubiquitin ligases HUWE1 and NEDD4 cooperatively control signal dependent PRC2-Ezh1 a/b mediated adaptive stress response pathway in skeletal muscle cells (2019). Liu P, Shuaib M,Zhang H, Nadeef S, Orlando V.Epigenetics & Chromatin12,78 (2019) doi:10.1186/s13072-019-0322-5. 
• AGO1 in association with NEAT1 lncRNA contributes to nuclear and 3D chromatin architecture in human cells (2019). Shuaib M,Parsi K.M, Kawaji H, Fort A, Adroub S.A, Thimma M, Ghosheh Y, Yamazaki T, Mannen T, Seridi L, Fallatah B, Carninci P, Hirose T, and Orlando V. BioRxiv. doi: https://doi.org/10.1101/525527
• The Flexible Ends of CENP-A Nucleosome Are Required for Mitotic Fidelity. (2016).Roulland Y, Ouararhni K, Naidenov M, Ramos L, Shuaib M,Syed SH, Lone IN, Boopathi R, Fontaine E, Papai G, Tachiwana H, Gautier T, Skoufias D, Padmanabhan K, Bednar J, Kurumizaka H, Schultz P, Angelov D, Hamiche A, Dimitrov S. Molecular Cell. 63 (4): 674-85.
• Phosphorylation of the CENP-A amino-terminus in mitotic centromeric chromatin is required for kinetochore function. (2013).  Goutte-Gattat* D, Shuaib M*,Ouararhni K*, Gautier T, Skoufias D.A, Hamiche A, Dimitrov S. Proc Natl Acad Sci USA. 110 (21): 8579-8584.(*Equal first author). 
• Chaperoning the histone H3 family. (2012).Hamiche A and Shuaib M. BBA-Gene Regulatory Mechanisms. 1819 (3-4): 230-237. 
• HJURP binds CENP-A via a highly conserved N-terminal domain and mediates its deposition at centromeres. (2010). Shuaib M,Ouararhni K, Dimitrov S, Hamiche A. Proc Natl Acad Sci USA. 107(4): 1349-1354.
• The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3. (2010).  Drané P, Ouararhni K, Depaux A, Shuaib M,Hamiche A. Genes & Development. 24(12): 1253-1265.