Olga Douvropoulou

PhD Students

PhD Candidate





Olga obtained her Bachelor's degree in Biology from the University of Athens (graduating in the top 2%) and continued her postgraduate studies at KAUST. She was top-ranking student in PhD courses. After joining the Pathogen Genomics Lab at KAUST, she has been studying host-pathogen interactions and the role of specific proteins of interest in mitochondrial metabolism, by employing a range of molecular biology techniques, including CRISPR/Cas9 technology, transcriptomics & proteomics.

Research Interests

Host-pathogen interactions

Multi‑omics approaches to identify candidate biomarkers and drug targets for pathogenic organisms

Post-transcriptional gene regulation across parasitic diseases and therapeutics targets

Selected Publications

  • Gornik, S. G., Flores, V., Reinhardt, F., Erber, L., Douvropoulou, O., Lassadi, I., Einarsson, E., Morl, M., Git, A., Stadler, P., Pain, A., & Waller, R. F. (2022). Mitochondrial genomes in Perkinsus decode conserved frameshifts in all genes. Molecular Biology and Evolution 39, 10, October (2022). https://doi.org/10.1093/molbev/msac191
  • Mourier, Shuaib, M., Hala, S., Mfarrej, S., Alofi, F., Naeem, R., Alsomali, A., Jorgensen, D., Subudhi, A. K., Ben Rached, F., Guan, Q., Salunke, R. P., Ooi, A., Esau, L., Douvropoulou, O., Nugmanova, R., Perumal, S., Zhang, H., Rajan, I., … Pain, A. (2022). SARS-CoV-2 genomes from Saudi Arabia implicate nucleocapsid mutations in host response and increased viral load. Nat Commun 13, 601 (2022). https://doi.org/10.1038/S41467-022-28287-8
  • Tobias Mourier, Denise Anete Madureira de Alvarenga, Abhinav Kaushik, Anielle de Pina-Costa, Olga Douvropoulou, Qingtian Guan, Francisco J. Guzmán-Vega, Sarah Forrester, Filipe Vieira Santos de Abreu, Cesare Bianco Júnior, Julio Cesar de Souza Junior, Silvia Bahadian Moreira, Zelinda Maria Braga Hirano, Alcides Pissinatti, Maria de Fátima Ferreira-da-Cruz, Ricardo Lourenço de Oliveira, Stefan T. Arold, Daniel C. Jeffares, Patrícia Brasil, Cristiana Ferreira Alves de Brito, Richard Culleton, Cláudio Tadeu Daniel-Ribeiro, Arnab Pain. The genome of the zoonotic malaria parasite reveals adaptations to host-switching.  BMC Biol 19, 219 (2021). https://doi.org/10.1186/s12915-021-01139-5
  • Ramaprasad, A., Klaus, S., Douvropoulou, O., Culleton, R. \& Pain, A. Plasmodium vinckei genomes provide insights into the pan-genome and evolution of rodent malaria parasites. BMC Biol 19, 69 (2021). https://doi.org/10.1186/s12915-021-00995-5
  • Meenakshi A Belekar, Tejashree Hingamire, Alok Tanala Patra, Olga Douvropoulou, Amit Kumar Subudhi, Raeece Naeem, Arnab Pain, Rajesh Chandramohandas, Dhanasekaran Shanmugam. Forward chemical-genetic screening on T. gondii gives an insight into molecular mechanism of delayed death phenotype using Pathogen Box molecules. (under preparation)


PhD in Biosciences, KAUST

Research Interests Keywords

Biological networks and interactions gene editing functional genomics Infectious diseases