I am interested in the genetic analysis of pathogens (bacteria & parasites) to understand their biological functions and diversity, using next generation sequencing technologies.
Selected Publications
AK Subudhi, JL Green, R Satyam, RP Salunke, T Lenz, M Shuaib, et al., DNA-binding protein PfAP2-P regulates parasite pathogenesis during malaria parasite blood stages, Nature Microbiology, 1-16, 2023, 10.1038/s41564-023-01497-6
M Shuaib, S Adroub, T Mourier, S Mfarrej, H Zhang, L Esau, A Alsomali, et al., Impact of the SARS-CoV-2 nucleocapsid 203K/204R mutations on the inflammatory immune response in COVID-19 severity, Genome Medicine, 15 (1), 54, 2023, 10.1186/s13073-023-01208-0
M Haidar, S Tajeri, L Momeux, T Mourier, F Ben-Rached, S Mfarrej, et al., miR-34c-3p Regulates Protein Kinase A Activity Independent of cAMP by Dicing prkar2b Transcripts in Theileria annulata-Infected Leukocytes, Msphere, 8 (2), e00526-22, 2023, 10.1128/msphere.00526-22
A Zuccolo, S Mfarrej, M Celii, S Mussurova, LF Rivera, V Llaca, et al., The gyrfalcon (Falco rusticolus) genome, G3: Genes, Genomes, Genetics 13 (3), jkad001, 2023, 10.1093/g3journal/jkad001
S Tajeri, L Momeux, B Saintpierre, S Mfarrej, A Chapple, T Mourier, et al., Theileria annulata histone deacetylase 1 (TaHDAC1) initiates schizont to merozoite stage conversion, Scientific Reports, 12 (1), 12710, 2022, 10.1038/s41598-022-15518-7
Q Guan, B Alhuthali, S Mfarrej, MA Halim, RS Almaghrabi, A Pain, Metagenomics-driven rapid diagnosis of an imported fatal case of rare amoebic meningoencephalitis, Journal of Travel Medicine, 29 (4), taab172, 2022, 10.1093/jtm/taab172
A Kaushik, DP Roberts, A Ramaprasad, S Mfarrej, M Nair, DK Lakshman, et al., Pangenome analysis of the soilborne fungal phytopathogen Rhizoctonia solani and development of a comprehensive web resource: RsolaniDB, Frontiers in microbiology, 13, 839524, 2022, 10.3389/fmicb.2022.839524
Q Guan, M Garbati, S Mfarrej, T AlMutairi, T Laval, A Singh, S Fagbo, et al., Insights into the ancestry evolution of the Mycobacterium tuberculosis complex from analysis of Mycobacterium riyadhense, NAR genomics and bioinformatics, 3 (3), lqab070, 2021, 10.1093/nargab/lqab070
F Gonzalez, J Johny, WB Walker III, Q Guan, S Mfarrej, J Jakše, et al., Antennal transcriptome sequencing and identification of candidate chemoreceptor proteins from an invasive pest, the American palm weevil, Rhynchophorus palmarum, Scientific reports, 11 (1), 8334, 2021, 10.1038/s41598-021-96402-8
C Bi, G Ramos-Mandujano, Y Tian, S Hala, J Xu, S Mfarrej, CR Esteban, et al., Simultaneous detection and mutation surveillance of SARS-CoV-2 and multiple respiratory viruses by rapid field-deployable sequencing, Med, 2 (6), 689-700. e4, 2021, 10.1016/j.medj.2021.03.015
G Ramos‐Mandujano, R Salunke, S Mfarrej, AT Rachmadi, S Hala, J Xu, et al., A robust, safe, and scalable magnetic nanoparticle workflow for RNA extraction of pathogens from clinical and wastewater samples, Global Challenges, 5 (4), 2000068, 2021, 10.1002/gch2.202000068
GR Mandujano, RP Salunke, S Mfarrej, AT Rachmadi, S Hala, J Xu, et al., A Robust, Safe, and Scalable Magnetic Nanoparticle Workflow for RNA Extraction of Pathogens from Clinical and Wastewater Samples, Wiley, 2021, 10.1002/gch2.202000068
Q Guan, M Sadykov, S Mfarrej, S Hala, R Naeem, R Nugmanova, et al., A genetic barcode of SARS-CoV-2 for monitoring global distribution of different clades during the COVID-19 pandemic, International Journal of Infectious Diseases, 100, 216-223, 2020, 10.1016/j.ijid.2020.08.052
K Tretina, M Haidar, SA Madsen-Bouterse, T Sakura, S Mfarrej, L Fry, et al., Theileria parasites subvert E2F signaling to stimulate leukocyte proliferation, Scientific reports, 10 (1), 3982, 2020, 10.1038/s41598-020-60939-x
Z Rchiad, M Haidar, HR Ansari, S Tajeri, S Mfarrej, F Ben Rached, et al., Novel tumour suppressor roles for GZMA and RASGRP1 in Theileria annulata‐transformed macrophages and human B lymphoma cells, Cellular Microbiology, 22 (12), e13255, 2020
C Bi, G Ramos Mandujano, S Hala, J Xu, S Mfarrej, FS Alofi, A Khogeer, et al., Multiplex Isothermal Amplification Coupled with Nanopore Sequencing for Rapid Detection and Mutation Surveillance of SARS-CoV-2, Cold Spring Harbor Laboratory, 2020
Education
Masters degree in Microbiology, Wagner College, New York, 2016
Bachelors degree in Biology, Wagner College, New York, 2014
